GTX61772-产品快照
- 品牌:
- GTX61772
- 型号:
- GTX61772
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产品介绍
GTX61772
Genetex - GTX61772 - p27/Kip1 (phospho Ser10) antibody [EP233(2)Y] (Each (100µl))
GTX61772
p27(Kip1) is a cyclin-dependent kinase inhibitor involved in G1 arrest. p27(Kip1) binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4 . p27(Kip1) is regulated by phosphorylation on serine 10 (S10) and threonine 187 (T187). Phosphorylation by CDK2 on T187 results in ubiquitylation and degradation of p27(Kip1) ; while phosphorylation by hKIS on S10 signals the nuclear export to the cytoplasm . This listing is for Each (100µl) See other products in some related categories (click to browse): Industrial & Scientific > Installation Test & Maintenance > Test Equipment > Laboratory Supplies Antigen P27/KIP1 (Phospho SER10) Host Rabbit Reactivity Human, Mouse, Rat Clone EP233(2)Y Isotype IgG Molecular Weight 27 kDa Unit Each (100µl) Application Note Recommended Starting Dilutions: For WB: Use at a dilution of 1:1, 000 - 10, 000 For IHC: Use at a dilution of 1:100 For IP: Use at a dilution of 1:30 Optimal working dilution for a specific application should be determined by the investigator. ChIP No ELISA No Flow Cytometry No Gel Shift No Immunochemistry Yes Immunofluorescence No Immunogen A phospho specific peptide corresponding to residues surrounding Serine 10 of human p27 was used as an immunogen. Immunoprecipitation Yes Monoclonal/Polyclonal Monoclonal Neutralization No Purification Cell Supernatant Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Storage Instruction Store at -20 °C. Stable for 12 months from date of receipt. Tested Applications IHC-P, IHC-M, IP, WB Type Primary Western Blot Yes
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