AG25B0005C100-产品快照
- 品牌:
- AG25B0005C100
- 型号:
- AG25B0005C100
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产品介绍
AG25B0005C100
AdipoGen - AG25B0005C100 - anti-NLRP1/NALP1 (human), pAb (AL176) (Each (100µG))
AG25B0005C100
NALP1/NLRP1 is able to form cytoplasmic structures termed death effector filaments. It enhances and stimulates apoptosis through activation of different caspase cascades. It is involved in the activation of caspase-1 and caspase-5 as part of the NALP1 inflammasome complex which leads to processing and release of IL1B and IL18._x000D_ Genetic variations in the NALP1/NLRP1 gene are associated with susceptibility to vitiligo-associated multiple autoimmune disease type 1, an autoimmune disorder characterized by the association of vitiligo with several autoimmune and autoinflammatory diseases including autoimmune thyroid disease, rheumatoid arthritis and systemic lupus erythematosus. This listing is for Each (100µG) See other products in some related categories (click to browse): Industrial & Scientific > Laboratory & Science Host Rabbit Form Liquid. Size 100 µg Unit Each (100µG) Applications WB Clonality Polyclonal Antibody Concentration 1 mg/ml Immunogen Synthetic peptide corresponding to aa 2-25 (A2GGAWGRLACYLEFLKKEELKEFQ25) at the N-terminus of human NLRP1/NALP1. Long Term Storage -20°C Short Term Storage +4°C Species Crossreactivity Human Specificity Recognizes human NLRP1/NALP1. Does not cross-react with mouse NLRP1/NALP1. Stability Stable for at least 1 year after receipt when stored at -20°C. Storage Buffer In PBS containing 10% glycerol and 0.02% sodium azide.
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